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HealingSubcutaneous

TB-500

Also known as: Thymosin Beta-4 fragment · TB4 · Tβ4

Synthetic fragment of thymosin beta-4. Binds G-actin, promotes actin polymerization, and upregulates cell migration, angiogenesis, and stem cell recruitment to damaged tissue.

At a glance

Half-life
2 days
Common route
Subcutaneous
Typical dose range
2,000–5,000mcg
Stability (reconstituted)
30days refrigerated

Best timing

Common protocol: 2–2.5 mg twice weekly for 4–6 weeks loading, then 2 mg weekly maintenance.

Contraindications

  • Active malignancy (cell migration enhancement)
  • Pregnancy
  • Bleeding disorders (theoretical platelet effects)

Watch symptoms

  • Temporary fatigue or 'flu-like' feeling during loading phase
  • Injection site soreness
  • Headache
  • Lightheadedness early in protocol

Citations

The primary literature.

  1. 01Thymosin beta 4: a multi-functional regenerative peptide. Basic properties and clinical applicationsPubMed
  2. 02Thymosin beta 4 promotes angiogenesis, wound healing, and hair follicle developmentPubMed

Related protocols

Stacks that use TB-500.

BPC + TB-500 Healing Stack

Eight-week soft-tissue and joint repair protocol.

View protocol
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