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HealingSubcutaneous

GHK-Cu

Also known as: Copper Peptide · Copper Tripeptide-1 · Glycyl-L-histidyl-L-lysine-copper

Tripeptide-copper complex that modulates over 4,000 genes toward a youthful expression pattern. Stimulates collagen and glycosaminoglycan synthesis, promotes wound healing, and exhibits antioxidant activity.

At a glance

Half-life
30 minutes
Common route
Subcutaneous
Typical dose range
1,000–3,000mcg
Stability (reconstituted)
14days refrigerated

Best timing

Often dosed daily. Topical and injectable routes used in parallel for wound healing protocols.

Contraindications

  • Wilson's disease or copper-overload conditions
  • Active melanoma (theoretical pigmentation pathway interaction)
  • Pregnancy

Watch symptoms

  • Hyperpigmentation at injection sites
  • Bluish discoloration if dose is excessive (copper)
  • Skin irritation with topical use
  • Metallic taste

Citations

The primary literature.

  1. 01GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin RegenerationPubMed
  2. 02GHK-Cu may Prevent Oxidative Stress in Skin by Regulating Copper and Modifying Expression of Numerous Antioxidant GenesPubMed

Related protocols

Stacks that use GHK-Cu.

GHK-Cu Aesthetic Stack

Sixteen-week copper-peptide protocol for hair density and skin quality.

View protocol

Anti-Aging Longevity

Multi-axis longevity protocol targeting pineal, mitochondrial, and dermal aging.

View protocol
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