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GH SecretagogueSubcutaneous

PEG-MGF

Also known as: PEGylated Mechano Growth Factor · Pegylated MGF

MGF conjugated to polyethylene glycol to extend its half-life from minutes to hours. Allows systemic dosing rather than purely local intramuscular injection. Same satellite-cell activation mechanism as native MGF.

At a glance

Half-life
2 days
Common route
Subcutaneous
Typical dose range
200–500mcg
Stability (reconstituted)
21days refrigerated

Best timing

Typically 2–3x weekly, dosed post-training on workout days. Avoid mixing in same syringe with insulin or IGF-1 LR3.

Contraindications

  • Active cancer
  • Pregnancy
  • Diabetic retinopathy
  • Severe hypoglycemia history

Watch symptoms

  • Injection site reactions (PEG can be irritating)
  • Mild hypoglycemia
  • Possible immunogenicity over time (anti-PEG antibodies)
  • Localized muscle fullness

Citations

The primary literature.

  1. 01PEGylation of mechano growth factor produces a long-acting muscle-stimulatory analogPubMed
  2. 02Mechano growth factor and its peptide derivatives: a reviewPubMed
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