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CognitiveIntranasal

N-Acetyl Selank

Also known as: NA-Selank · Acetyl-Selank

Acetylated analog of Selank with improved stability and longer duration of action. Same heptapeptide tuftsin backbone — anxiolytic effects via GABA-A modulation and enkephalin system regulation without sedation in animal models.

At a glance

Half-life
1 hours
Common route
Intranasal
Typical dose range
250–1,500mcg
Stability (reconstituted)
30days refrigerated

Best timing

Intranasal, 1–3x daily. Lower frequency than plain Selank due to longer half-life; can also be used acutely before stress.

Contraindications

  • Pregnancy
  • Concurrent benzodiazepine use without supervision
  • Limited human trial data — most evidence extrapolated from Selank research

Watch symptoms

  • Mild nasal irritation
  • Headache
  • Sedation at higher doses
  • Emotional blunting with chronic use

Citations

The primary literature.

  1. 01Selank: pharmacological action and the perspectives of its usePubMed
  2. 02Effect of Selank on GABA-receptor subunit gene expression in the rat hippocampusPubMed
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