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AestheticSubcutaneous
Melanotan II
Also known as: MT-II · MT2 · Melanotan 2
Synthetic alpha-MSH analog with non-selective melanocortin receptor agonism (MC1R for pigmentation, MC3/4R for appetite and libido). Stimulates eumelanin production and produces a tanning response without UV exposure.
At a glance
- Half-life
- 33 hours
- Common route
- Subcutaneous
- Typical dose range
- 250–1,000mcg
- Stability (reconstituted)
- 30days refrigerated
Best timing
Loading phase: 250–500 mcg nightly until desired pigmentation. Maintenance: 1–2x weekly. Mole and skin check before starting.
Contraindications
- Personal or family history of melanoma
- Atypical or numerous moles
- Cardiovascular disease
- Pregnancy
- Untreated hypertension
Watch symptoms
- Nausea (especially first doses — dose before bed)
- Spontaneous erections, increased libido
- Darkening of existing moles
- Appetite suppression
- Facial flushing, blood pressure changes
- New pigmented lesions — dermatology check required
Citations